doi: 10.3390/children11010044
Deformability Optimization: Integrating biocompatible edge activators to lower the elastic modulus of the membrane, enabling the vesicles to physically squeeze through the stratum corneum via intercellular pathways
While Epitalon resets the body internal clock by restoring melatonin production, Pinealon calms the mind and stabilizes the brain bioenergetic environment
Our results showed that the BBB hindered the delivery of the drugs to the tumor and drastically affected the overall drug efficacy
I think they are promising but Im not sold just yet for me personally because of the lack of data and regulation
This review provides a comprehensive overview of the interplay between vascular stability, CBF regulation, and vascular inflammation in the context of the BBB, with a particular emphasis on the dysfunction of these mechanisms in the pathophysiology of neurodegenerative diseases such as AD, PD, ALS, and MS